|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
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gptkb:DLK
gptkb:Dual_leucine_zipper-bearing_kinase
gptkb:Mitogen-activated_protein_kinase_kinase_kinase_12
|
|
gptkbp:associatedWith
|
apoptosis
neuronal development
axon regeneration
|
|
gptkbp:discoveredBy
|
gptkb:Nishitoh_et_al.
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
gptkb:Mitogen-activated_protein_kinase_kinase_kinase_12_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000111321
7786
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
brain
|
|
gptkbp:function
|
serine/threonine protein kinase activity
involved in MAPK signaling pathway
involved in axon growth
regulates neuronal apoptosis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
6840
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAP3K12
|
|
gptkbp:interactsWith
|
gptkb:MAP2K7
JNK pathway proteins
|
|
gptkbp:length
|
1030 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12
|
|
gptkbp:molecularWeight
|
114 kDa
|
|
gptkbp:OMIM
|
604437
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Map3k12
|
|
gptkbp:phosphorylates
|
gptkb:MAP2K4
gptkb:MAP2K7
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q12852
|
|
gptkbp:bfsParent
|
gptkb:MAP2K3
gptkb:DLK
|
|
gptkbp:bfsLayer
|
7
|