Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:receptor_tyrosine_kinases
small GTPases stress signals |
| gptkbp:alternativeName |
gptkb:MAP3K
|
| gptkbp:domain |
protein kinase domain
|
| gptkbp:downstreamOf |
gptkb:MAPKK
gptkb:MAP4K |
| gptkbp:enzymeClassification |
EC 2.7.11.25
|
| gptkbp:example |
gptkb:TAK1
gptkb:Raf gptkb:MEKK1 ASK1 |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
gptkb:Mitogen-activated_protein_kinase_kinase_kinase
|
| gptkbp:function |
phosphorylates MAPKK
|
| gptkbp:GO_term |
GO:0004709
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAPKKK
|
| gptkbp:involvedIn |
gptkb:MAPK_signaling_pathway
|
| gptkbp:regulates |
MAPK cascade
|
| gptkbp:role |
apoptosis
cell proliferation differentiation inflammation cellular response to stress |
| gptkbp:bfsParent |
gptkb:Ras/MAPK_signaling_pathway
|
| gptkbp:bfsLayer |
6
|