Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:associatedWith |
gptkb:cancer
autoimmune diseases |
| gptkbp:discoveredIn |
1995
|
| gptkbp:encodes |
Mitogen-activated protein kinase kinase kinase 8
|
| gptkbp:Entrez_Gene_ID |
1326
|
| gptkbp:expressedIn |
gptkb:T_cells
macrophages immune cells |
| gptkbp:function |
gptkb:MAPK_signaling_pathway
serine/threonine kinase activity |
| gptkbp:HGNC_ID |
6840
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAP3K8
|
| gptkbp:involvedIn |
immune response
inflammatory response |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_10
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Map3k8
|
| gptkbp:otherName |
gptkb:COT
TPL2 |
| gptkbp:phosphorylates |
gptkb:MAP2K
gptkb:IKK_complex |
| gptkbp:regulates |
cytokine production
ERK1/2 pathway NF-kappaB signaling activated by IL-1 activated by LPS activated by TNF-alpha |
| gptkbp:UniProtID |
P41279
|
| gptkbp:bfsParent |
gptkb:MAP2K3
|
| gptkbp:bfsLayer |
7
|