|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:HRAS
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:chromosomeArm
|
gptkb:11p15.5
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:encodes
|
gptkb:GTPase_HRas
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000174775
3265
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:firstDescribed
|
gptkb:Weinberg_et_al.
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
cell differentiation
signal transduction
cell growth regulation
|
|
gptkbp:HGNC_ID
|
5173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
c-Ha-ras
|
|
gptkbp:length
|
189 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 11
|
|
gptkbp:memberOf
|
gptkb:RAS_gene_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:Costello_syndrome
oncogenic
bladder cancer
codon 12
codon 61
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:product
|
gptkb:HRas_protein
|
|
gptkbp:proteinFamily
|
small molecule
|
|
gptkbp:regulates
|
gptkb:MAPK/ERK_pathway
gptkb:PI3K/AKT_pathway
|
|
gptkbp:UniProtID
|
gptkb:P01112
|
|
gptkbp:bfsParent
|
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkb:Hras1
gptkb:human_HRAS
gptkb:human_HRAS_gene
|
|
gptkbp:bfsLayer
|
6
|