|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
gptkb:apoptosome
gptkb:death-inducing_signaling_complex
proteolytic cleavage
|
|
gptkbp:activeSiteResidue
|
cysteine
|
|
gptkbp:cleavage
|
aspartic acid
|
|
gptkbp:discoveredBy
|
gptkb:Yuan_J
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:EC_number
|
3.4.22
|
|
gptkbp:foundIn
|
animals
|
|
gptkbp:function
|
gptkb:protease
apoptosis regulation
|
|
gptkbp:GO_term
|
GO:0004197
|
|
gptkbp:hasMember
|
gptkb:Caspase-9
gptkb:Caspase-3
gptkb:Caspase-1
gptkb:Caspase-10
gptkb:Caspase-12
gptkb:Caspase-14
gptkb:Caspase-2
gptkb:Caspase-4
gptkb:Caspase-5
gptkb:Caspase-6
gptkb:Caspase-7
gptkb:Caspase-8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Caspase
|
|
gptkbp:inhibitedBy
|
gptkb:IAP_proteins
gptkb:z-VAD-fmk
|
|
gptkbp:involvedIn
|
inflammation
cell death
|
|
gptkbp:namedAfter
|
cysteine-aspartic protease
|
|
gptkbp:relatedTo
|
programmed cell death
inflammatory response
|
|
gptkbp:significance
|
gptkb:cancer
neurodegenerative diseases
autoimmune diseases
|
|
gptkbp:structure
|
heterodimer
|
|
gptkbp:subclassOf
|
gptkb:cysteine_protease
|
|
gptkbp:UniProtID
|
Proteases
|
|
gptkbp:bfsParent
|
gptkb:Enzymes
|
|
gptkbp:bfsLayer
|
6
|