death-inducing signaling complex
GPTKB entity
Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:DISC
|
| gptkbp:component |
gptkb:FADD
gptkb:procaspase-8 gptkb:Fas_receptor procaspase-10 |
| gptkbp:discoveredBy |
1995
|
| gptkbp:formedBy |
ligand binding to death receptor
|
| gptkbp:function |
initiates apoptosis
|
| https://www.w3.org/2000/01/rdf-schema#label |
death-inducing signaling complex
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:relatedTo |
gptkb:TNF_receptor
TRAIL receptor extrinsic apoptotic pathway |
| gptkbp:role |
gptkb:cancer
autoimmune disorders |
| gptkbp:bfsParent |
gptkb:Caspase
|
| gptkbp:bfsLayer |
7
|