Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
proteolytic processing
|
| gptkbp:activeSiteResidue |
cysteine
|
| gptkbp:alternativeName |
Mch2
CASP-6 apoptotic protease Mch-2 |
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
gptkb:Huntington's_disease neurodegeneration |
| gptkbp:biologicalProcess |
proteolysis
|
| gptkbp:CASNumber |
187389-52-2
|
| gptkbp:cellularComponent |
gptkb:nucleus
cytosol |
| gptkbp:EC_number |
3.4.22.59
|
| gptkbp:encodedBy |
CASP6 gene
|
| gptkbp:function |
gptkb:cysteine_protease
apoptosis |
| https://www.w3.org/2000/01/rdf-schema#label |
Caspase-6
|
| gptkbp:involvedIn |
cleavage of cytoskeletal proteins
cleavage of nuclear proteins |
| gptkbp:locatedOnChromosome |
chromosome 4q25
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:relatedTo |
gptkb:caspase_family
|
| gptkbp:structure |
heterotetramer
|
| gptkbp:substrate |
gptkb:PARP
gptkb:lamin_A keratin |
| gptkbp:UniProtID |
P55212
|
| gptkbp:bfsParent |
gptkb:Caspase
|
| gptkbp:bfsLayer |
7
|