Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
IL-18 processing
IL-1β processing |
| gptkbp:alternativeName |
gptkb:ICH3
CASP-5 ICE(rel)III |
| gptkbp:cleavesAfter |
aspartic acid residue
|
| gptkbp:discoveredIn |
1997
|
| gptkbp:EC_number |
3.4.22.58
|
| gptkbp:encodedBy |
CASP5 gene
|
| gptkbp:family |
gptkb:caspase_family
|
| gptkbp:form |
heterotetramer
|
| gptkbp:function |
gptkb:cysteine_protease
inflammatory response |
| https://www.w3.org/2000/01/rdf-schema#label |
Caspase-5
|
| gptkbp:involvedIn |
apoptosis
pyroptosis |
| gptkbp:locatedIn |
gptkb:human
|
| gptkbp:locatedOnChromosome |
gptkb:human_chromosome_11
|
| gptkbp:molecularWeight |
~49 kDa
|
| gptkbp:orthologIn |
mouse Caspase-11
|
| gptkbp:participatedIn |
non-canonical inflammasome pathway
|
| gptkbp:product |
CASP5 gene
|
| gptkbp:relatedTo |
gptkb:Caspase-1
gptkb:Caspase-4 |
| gptkbp:subcellularLocation |
cytosol
|
| gptkbp:UniProtID |
P51878
|
| gptkbp:bfsParent |
gptkb:Caspase
|
| gptkbp:bfsLayer |
7
|