Statements (22)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:chemical_compound
caspase inhibitor |
gptkbp:application |
neuroscience research
immunology research cell death research |
gptkbp:CASNumber |
187389-52-2
|
gptkbp:chemicalFormula |
C26H29FN6O4
|
gptkbp:effect |
blocks apoptosis
prevents caspase activation |
https://www.w3.org/2000/01/rdf-schema#label |
z-VAD-fmk
|
gptkbp:inhibitedBy |
gptkb:caspase-8
gptkb:caspase-1 gptkb:caspase-9 gptkb:caspase-3 gptkb:caspase-7 |
gptkbp:mechanismOfAction |
irreversible pan-caspase inhibitor
|
gptkbp:molecularWeight |
508.55 g/mol
|
gptkbp:synonym |
benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone
|
gptkbp:target |
cysteine proteases
|
gptkbp:usedFor |
apoptosis inhibitor
|
gptkbp:bfsParent |
gptkb:Caspase
|
gptkbp:bfsLayer |
7
|