Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
lipopolysaccharide
|
| gptkbp:alternativeName |
ICErel-II
ICH-2 caspase-4 precursor |
| gptkbp:biologicalProcess |
cysteine-type endopeptidase activity
|
| gptkbp:cleavage |
gasdermin D
|
| gptkbp:discoveredIn |
1996
|
| gptkbp:EC_number |
3.4.22.57
|
| gptkbp:encodedBy |
CASP4 gene
|
| gptkbp:expressedIn |
dendritic cells
macrophages monocytes |
| gptkbp:function |
gptkb:protease
inflammatory caspase |
| https://www.w3.org/2000/01/rdf-schema#label |
Caspase-4
|
| gptkbp:involvedIn |
apoptosis
innate immune response pyroptosis |
| gptkbp:locatedOnChromosome |
chromosome 11q22.2-q22.3
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:relatedTo |
gptkb:caspase-1
caspase-11 (mouse ortholog) caspase-5 |
| gptkbp:UniProtID |
P49662
|
| gptkbp:bfsParent |
gptkb:Caspase
|
| gptkbp:bfsLayer |
7
|