plasmacytoid dendritic cells

URI: https://gptkb.org/entity/plasmacytoid_dendritic_cells
GPTKB entity
Statements (51)
Predicate Object
gptkbp:instanceOf immune response
gptkbp:abundantIn gptkb:thymus
lymph nodes
spleen
peripheral blood
gptkbp:activatedBy gptkb:natural_killer_cells
gptkb:B_cells
gptkb:T_cells
gptkbp:alsoKnownAs pDCs
gptkbp:derivedFrom bone marrow
gptkbp:doNotExpress gptkb:CD11c
gptkb:CD56
gptkb:CD20
gptkb:CD34
gptkb:CD3
gptkb:CD19
gptkb:CD14
CD16
CD235a
gptkbp:expressedIn gptkb:CD123
gptkb:CD303
gptkb:CD304
gptkb:BDCA-2
gptkb:TLR9
TLR7
gptkbp:firstDescribed 1958
gptkbp:foundIn blood
lymphoid tissues
gptkbp:function antigen presentation
antiviral defense
https://www.w3.org/2000/01/rdf-schema#label plasmacytoid dendritic cells
gptkbp:involves gptkb:systemic_lupus_erythematosus
autoimmune diseases
viral infections
gptkbp:marking gptkb:CD4
gptkb:CD45RA
gptkb:HLA-DR
CD68
gptkbp:morphologicalType plasma cell-like
gptkbp:produces gptkb:type_I_interferons
gptkbp:response RNA viruses
CpG DNA
viral nucleic acids
gptkbp:role innate immunity
adaptive immunity
gptkbp:secretes gptkb:interferon-beta
gptkb:interferon-alpha
gptkb:interleukin-6
gptkb:tumor_necrosis_factor-alpha
gptkbp:bfsParent gptkb:CD304
gptkbp:bfsLayer 7