plasmacytoid dendritic cells

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:immune_response
gptkbp:abundantIn	gptkb:thymus lymph nodes spleen peripheral blood
gptkbp:activatedBy	gptkb:natural_killer_cells gptkb:B_cells gptkb:T_cells
gptkbp:alsoKnownAs	pDCs
gptkbp:derivedFrom	bone marrow
gptkbp:doNotExpress	gptkb:CD11c gptkb:CD56 gptkb:CD20 gptkb:CD34 gptkb:CD3 gptkb:CD19 gptkb:CD14 CD16 CD235a
gptkbp:expressedIn	gptkb:CD123 gptkb:CD303 gptkb:CD304 gptkb:BDCA-2 gptkb:TLR9 TLR7
gptkbp:firstDescribed	1958
gptkbp:foundIn	blood lymphoid tissues
gptkbp:function	antigen presentation antiviral defense
gptkbp:involves	gptkb:systemic_lupus_erythematosus autoimmune diseases viral infections
gptkbp:marking	gptkb:CD4 gptkb:CD45RA gptkb:HLA-DR CD68
gptkbp:morphologicalType	plasma cell-like
gptkbp:produces	gptkb:type_I_interferons
gptkbp:response	RNA viruses CpG DNA viral nucleic acids
gptkbp:role	innate immunity adaptive immunity
gptkbp:secretes	gptkb:interferon-beta gptkb:interferon-alpha gptkb:interleukin-6 gptkb:tumor_necrosis_factor-alpha
gptkbp:bfsParent	gptkb:CD123 gptkb:CD289 gptkb:CD303 gptkb:CD304 gptkb:CD378 gptkb:LAG-3 gptkb:B220 gptkb:LILRA4
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	plasmacytoid dendritic cells