|
gptkbp:instanceOf
|
gptkb:protein
gptkb:major_histocompatibility_complex_class_II_molecule
|
|
gptkbp:alternativeName
|
Human Leukocyte Antigen DR
|
|
gptkbp:associatedWith
|
multiple sclerosis
type 1 diabetes
autoimmune diseases
rheumatoid arthritis
|
|
gptkbp:component
|
immune system
|
|
gptkbp:discoveredIn
|
1970s
|
|
gptkbp:encodedBy
|
HLA-DRA gene
HLA-DRB1 gene
|
|
gptkbp:expressedIn
|
gptkb:B_cells
dendritic cells
macrophages
antigen-presenting cells
|
|
gptkbp:foundIn
|
humans
|
|
gptkbp:function
|
antigen presentation
|
|
gptkbp:hasAllele
|
gptkb:HLA-DR4
HLA-DR1
HLA-DR10
HLA-DR11
HLA-DR12
HLA-DR13
HLA-DR14
HLA-DR15
HLA-DR16
HLA-DR17
HLA-DR18
HLA-DR2
HLA-DR3
HLA-DR5
HLA-DR51
HLA-DR52
HLA-DR53
HLA-DR6
HLA-DR7
HLA-DR8
HLA-DR9
|
|
gptkbp:hasPolymorphism
|
true
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:location
|
cell surface
|
|
gptkbp:partOf
|
gptkb:HLA_system
|
|
gptkbp:recognizedBy
|
gptkb:CD4+_T_cells
|
|
gptkbp:structure
|
heterodimer
|
|
gptkbp:subunit
|
alpha chain
beta chain
|
|
gptkbp:usedIn
|
disease association studies
transplant compatibility testing
|
|
gptkbp:bfsParent
|
gptkb:HLA_genes
gptkb:HLA_complex_(human)
gptkb:MHC_class_II_molecules
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HLA-DR
|