systemic lupus erythematosus

GPTKB entity

Predicate	Object
gptkbp:instanceOf	autoimmune disease chronic disease
gptkbp:abbreviation	SLE
gptkbp:affects	multiple organ systems
gptkbp:autoantibody	gptkb:anti-La gptkb:anti-Ro gptkb:anti-Smith gptkb:anti-dsDNA gptkb:anti-phospholipid
gptkbp:cause	gptkb:anemia pericarditis thrombocytopenia neurological symptoms leukopenia pleuritis kidney inflammation
gptkbp:complication	gptkb:cardiovascular_disease stroke infections pregnancy complications lupus nephritis
gptkbp:diagnosedBy	gptkb:ANA_test gptkb:anti-dsDNA_antibody_test clinical criteria
gptkbp:firstDescribed	gptkb:Moritz_Kaposi
https://www.w3.org/2000/01/rdf-schema#label	systemic lupus erythematosus
gptkbp:ICD-10_code	gptkb:M32
gptkbp:MeSH_ID	D008180
gptkbp:OMIM	152700
gptkbp:onset_age	15-45 years
gptkbp:prevalence	more common in women more common in African Americans more common in Asians more common in Hispanics
gptkbp:riskFactor	genetic predisposition female sex hormonal factors environmental triggers
gptkbp:symptom	fever fatigue joint pain hair loss photosensitivity skin rash oral ulcers
gptkbp:treatment	gptkb:NSAIDs antimalarial drugs corticosteroids immunosuppressants
gptkbp:triggeredBy	certain medications sunlight infections
gptkbp:bfsParent	gptkb:cyclophosphamide gptkb:IL4 gptkb:autoimmune_hemolytic_anemia gptkb:C-reactive_protein gptkb:interleukin-6 gptkb:C-X-C_motif_chemokine_ligand_13 gptkb:Osler's_nodes gptkb:Cerebral_Venous_Thrombosis
gptkbp:bfsLayer	6