CD11c

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:protein
cell surface marker
gptkbp:alternativeName p150
ITGAX
integrin alpha X
leukocyte adhesion glycoprotein p150
gptkbp:component integrin alpha X beta 2
gptkbp:discoveredIn 1980s
gptkbp:encodedBy ITGAX gene
gptkbp:Entrez_Gene_ID 3687
gptkbp:expressedIn gptkb:cancer
liver
lymph nodes
spleen
bone marrow
activated T cells
peripheral blood
myeloid lineage cells
gptkbp:familyMember integrin family
gptkbp:formsComplexWith gptkb:CD18
gptkbp:foundIn dendritic cells
macrophages
monocytes
some NK cells
gptkbp:function immune response
phagocytosis
cell adhesion
gptkbp:HGNC_ID 6156
https://www.w3.org/2000/01/rdf-schema#label CD11c
gptkbp:interactsWith gptkb:ICAM-1
gptkb:fibrinogen
complement fragment iC3b
gptkbp:involvedIn antigen presentation
leukocyte migration
gptkbp:locatedOnChromosome gptkb:16p11.2
gptkbp:marking dendritic cells
gptkbp:molecularWeight 150 kDa
gptkbp:OMIM 151510
gptkbp:species gptkb:human
gptkb:mouse
right
gptkbp:structure transmembrane glycoprotein
gptkbp:subunit CR4 (complement receptor 4)
gptkbp:UniProtID P20702
gptkbp:usedIn immunophenotyping
immunohistochemistry
flow cytometry
gptkbp:bfsParent gptkb:dendritic_cell
gptkbp:bfsLayer 7