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gptkbp:instanceOf
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immune response
T cell subtype
|
|
gptkbp:alsoKnownAs
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gptkb:Th2_cells
|
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gptkbp:antigenRecognitionVia
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gptkb:MHC_class_II
|
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gptkbp:developedBy
|
naive CD4+ T cells
|
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gptkbp:differentiationRegulatedBy
|
gptkb:GATA3
gptkb:STAT6
IL-4 signaling
|
|
gptkbp:discoveredBy
|
gptkb:Tim_Mosmann
|
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gptkbp:discoveredIn
|
1986
|
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gptkbp:dysregulationAssociatedWith
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gptkb:systemic_lupus_erythematosus
gptkb:atopic_dermatitis
allergic rhinitis
food allergy
allergic diseases
|
|
gptkbp:enemyOf
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gptkb:interferon-gamma
T helper 1 cells
|
|
gptkbp:expressedIn
|
gptkb:GATA3
gptkb:CD4
|
|
gptkbp:function
|
inhibit Th1 cell responses
promote humoral immunity
stimulate B cell antibody production
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
T helper 2 cells
|
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gptkbp:inducedBy
|
gptkb:interleukin-4
|
|
gptkbp:involvedIn
|
asthma
allergic responses
helminth infection response
|
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gptkbp:location
|
lymph nodes
peripheral blood
mucosal tissues
|
|
gptkbp:marking
|
gptkb:CCR4
gptkb:CRTH2
gptkb:CD30
|
|
gptkbp:partOf
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gptkb:adaptive_immune_system
|
|
gptkbp:regulates
|
eosinophil activation
IgE class switching
mast cell activation
|
|
gptkbp:secretes
|
gptkb:interleukin-5
gptkb:interleukin-9
gptkb:interleukin-6
gptkb:interleukin-4
gptkb:interleukin-13
gptkb:interleukin-10
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:bfsParent
|
gptkb:IL13
gptkb:IL4
gptkb:IL5
|
|
gptkbp:bfsLayer
|
6
|