Statements (64)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:vaccine
|
| gptkbp:associated_with |
gptkb:asthma
allergic diseases |
| gptkbp:discovered_by |
gptkb:1980s
|
| gptkbp:established |
gptkb:mepolizumab
gptkb:reslizumab gptkb:benralizumab apoptosis of eosinophils |
| gptkbp:function |
promotes eosinophil differentiation
stimulates B cell growth |
| https://www.w3.org/2000/01/rdf-schema#label |
interleukin-5
|
| gptkbp:is_involved_in |
gptkb:eosinophilic_granulomatosis_with_polyangiitis
gptkb:healthcare_organization gptkb:Crohn's_disease gptkb:systemic_lupus_erythematosus gptkb:ulcerative_colitis gptkb:eosinophilic_fasciitis gptkb:psychologist gptkb:rheumatoid_arthritis immune response autoimmune diseases urticaria anaphylaxis food allergies mucosal immunity atopic dermatitis chronic obstructive pulmonary disease tissue remodeling skin allergies hypersensitivity reactions parasitic infections lung inflammation drug allergies environmental allergies hypereosinophilia eosinophilic esophagitis Ig E production allergic inflammation eosinophilic arthritis eosinophilic colitis eosinophilic conjunctivitis eosinophilic cystitis eosinophilic dermatitis eosinophilic hepatitis eosinophilic meningitis eosinophilic myocarditis eosinophilic myositis eosinophilic nephritis eosinophilic otitis media eosinophilic pancreatitis eosinophilic pneumonia eosinophilic scleritis eosinophilic sinusitis eosinophilic vasculitis gastrointestinal allergies |
| gptkbp:is_vulnerable_to |
gptkb:IL-5_receptor
|
| gptkbp:produced_by |
gptkb:T_cells
bone marrow |
| gptkbp:promoter |
I L5
|
| gptkbp:role |
Th2 immune response
|
| gptkbp:targets |
chronic rhinosinusitis
eosinophilic esophagitis |
| gptkbp:bfsParent |
gptkb:Fasenra
|
| gptkbp:bfsLayer |
4
|