Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:MHC_II
gptkb:class_II_MHC |
| gptkbp:binds |
peptide antigens
|
| gptkbp:component |
gptkb:major_histocompatibility_complex
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
gptkb:HLA-DP
gptkb:HLA-DQ gptkb:HLA-DR |
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
antigen presentation
|
| gptkbp:geneCluster |
gptkb:chromosome_6_(human)
|
| https://www.w3.org/2000/01/rdf-schema#label |
MHC class II
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:presentIn |
gptkb:B_cells
dendritic cells macrophages antigen-presenting cells |
| gptkbp:recognizedBy |
gptkb:CD4+_T_cells
|
| gptkbp:role |
autoimmune diseases
adaptive immune response transplant rejection |
| gptkbp:species |
gptkb:human
gptkb:mouse other mammals |
| gptkbp:structure |
heterodimer
|
| gptkbp:subunit |
alpha chain
beta chain |
| gptkbp:bfsParent |
gptkb:MHC_molecule
|
| gptkbp:bfsLayer |
6
|