|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:Ki-1_antigen
gptkb:TNFRSF8
|
|
gptkbp:associatedWith
|
leukemia
lymphoproliferative disorders
|
|
gptkbp:discoveredBy
|
gptkb:Hans_Stein
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:encodedBy
|
gptkb:TNFRSF8_gene
|
|
gptkbp:expressedIn
|
gptkb:Reed-Sternberg_cells
gptkb:anaplastic_large_cell_lymphoma_cells
activated T cells
|
|
gptkbp:function
|
regulation of apoptosis
regulation of cell proliferation
immune response modulation
|
|
gptkbp:HGNC_ID
|
11910
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD30
|
|
gptkbp:interactsWith
|
gptkb:TRAF_proteins
CD30 ligand (CD153)
|
|
gptkbp:locatedOnChromosome
|
gptkb:1p36
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:molecularWeight
|
120 kDa
|
|
gptkbp:OMIM
|
153243
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
type I transmembrane protein
|
|
gptkbp:target
|
gptkb:brentuximab_vedotin
|
|
gptkbp:UniProtID
|
gptkb:P28908
|
|
gptkbp:usedAs
|
diagnostic marker for Hodgkin lymphoma
diagnostic marker for anaplastic large cell lymphoma
|
|
gptkbp:bfsParent
|
gptkb:anaplastic_large_cell_lymphoma
gptkb:Hodgkin's_lymphoma
gptkb:Adcetris
gptkb:Reed-Sternberg_cell
gptkb:primary_mediastinal_large_B-cell_lymphoma
gptkb:primary_effusion_lymphoma
|
|
gptkbp:bfsLayer
|
6
|