|
gptkbp:instanceOf
|
cytokine
|
|
gptkbp:associatedWith
|
asthma
eosinophilia
|
|
gptkbp:category
|
cytokine
immune system protein
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:encodedBy
|
gptkb:IL5_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000113525
|
|
gptkbp:expressedIn
|
gptkb:mast_cells
gptkb:eosinophils
activated T cells
|
|
gptkbp:fullName
|
gptkb:Interleukin-5
|
|
gptkbp:function
|
stimulates growth and differentiation of eosinophils
promotes activation of eosinophils
stimulates B cell growth
|
|
gptkbp:gene
|
gptkb:IL5
|
|
gptkbp:GOID
|
gptkb:GO:0005126
|
|
gptkbp:HGNC_ID
|
6025
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL5
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
5q31.1
|
|
gptkbp:molecularWeight
|
~26 kDa
|
|
gptkbp:OMIM
|
147850
|
|
gptkbp:orthologInMouse
|
gptkb:Il5
|
|
gptkbp:PDB
|
gptkb:3VA2
|
|
gptkbp:producedBy
|
gptkb:mast_cells
gptkb:T_helper_2_cells
gptkb:eosinophils
|
|
gptkbp:recipient
|
gptkb:IL-5_receptor
|
|
gptkbp:RefSeq
|
gptkb:NM_000879
|
|
gptkbp:regulates
|
B cell antibody production
eosinophil activation
eosinophil survival
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:targetOfDrug
|
gptkb:benralizumab
gptkb:mepolizumab
gptkb:reslizumab
|
|
gptkbp:UniProtID
|
P05113
|
|
gptkbp:bfsParent
|
gptkb:chromosome_5
|
|
gptkbp:bfsLayer
|
5
|