|
gptkbp:instanceOf
|
T helper cell subtype
|
|
gptkbp:differentiationInducedBy
|
gptkb:IL-4
|
|
gptkbp:differentiationRegulatedBy
|
gptkb:GATA3
gptkb:STAT6
|
|
gptkbp:discoveredBy
|
Timothy Mosmann
|
|
gptkbp:enemyOf
|
gptkb:Th17_cells
gptkb:Th1_cells
|
|
gptkbp:expressedIn
|
gptkb:GATA3
gptkb:CCR4
gptkb:CD4
|
|
gptkbp:function
|
promote humoral immunity
coordinate immune response against extracellular parasites
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Th2 cells
|
|
gptkbp:inhibitedBy
|
macrophage activation
Th1 cell differentiation
|
|
gptkbp:involvedIn
|
gptkb:atopic_dermatitis
asthma
allergic response
helminth infection response
|
|
gptkbp:location
|
lymph nodes
peripheral blood
mucosal tissues
|
|
gptkbp:marking
|
gptkb:GATA3
gptkb:CCR4
gptkb:CD3
gptkb:CD4
|
|
gptkbp:promotion
|
eosinophil activation
IgE production
mast cell activation
|
|
gptkbp:regulates
|
B cell antibody class switching
|
|
gptkbp:role
|
asthma pathogenesis
tissue repair
allergic diseases
immunity to helminths
|
|
gptkbp:secretes
|
gptkb:IL-10
gptkb:IL-4
gptkb:IL-5
gptkb:IL-13
IL-9
|
|
gptkbp:subclassOf
|
gptkb:CD4+_T_cells
|
|
gptkbp:bfsParent
|
gptkb:CD4+_T_cells
|
|
gptkbp:bfsLayer
|
6
|