|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:cellular_tumor_antigen_p53
gptkb:antigen_NY-CO-13
gptkb:phosphoprotein_p53
gptkb:tumor_suppressor_p53
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Li-Fraumeni_syndrome
|
|
gptkbp:enzymeRegulation
|
regulated by MDM2
|
|
gptkbp:function
|
tumor suppressor
transcription factor
|
|
gptkbp:gene
|
gptkb:TP53
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P04626
|
|
gptkbp:interactsWith
|
gptkb:CDKN1A
gptkb:CREBBP
gptkb:EP300
gptkb:TP53BP1
gptkb:TP53INP1
gptkb:BAX
gptkb:MDM2
gptkb:BRCA1
ATM
|
|
gptkbp:length
|
393 amino acids
|
|
gptkbp:locatedOnChromosome
|
17p13.1
|
|
gptkbp:mainTerminal
|
gptkb:GO:0008285
GO:0003677
GO:0006974
GO:0006355
GO:0006915
|
|
gptkbp:molecularWeight
|
43.7 kDa
|
|
gptkbp:name
|
Tumor protein p53
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
apoptosis
DNA repair
senescence
cell cycle arrest
|
|
gptkbp:PDB
|
gptkb:2OCJ
gptkb:3KMD
1TUP
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:reviewedBy
|
yes
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:structure
|
tetramer
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P04626
|
|
gptkbp:bfsParent
|
gptkb:HER2/neu
gptkb:ERBB2
gptkb:HER2/neu_receptor
gptkb:HER2_receptor
gptkb:Her2
gptkb:HER2_protein
|
|
gptkbp:bfsLayer
|
7
|