|
gptkbp:instanceOf
|
gptkb:immune_response
gptkb:lymphocyte
|
|
gptkbp:abbreviation
|
gptkb:NK_cell
|
|
gptkbp:activatedBy
|
gptkb:interleukin-2
gptkb:interleukin-12
gptkb:interleukin-15
gptkb:interleukin-18
|
|
gptkbp:compatibleWith
|
antigen presentation
prior sensitization
|
|
gptkbp:developedBy
|
common lymphoid progenitor
|
|
gptkbp:expressedIn
|
gptkb:CD56
CD16
|
|
gptkbp:firstDescribed
|
1975
|
|
gptkbp:foundIn
|
gptkb:lymphoid_tissue
blood
|
|
gptkbp:function
|
cytotoxicity
immune surveillance
killing tumor cells
killing virus-infected cells
|
|
gptkbp:hasNo
|
gptkb:CD3
|
|
gptkbp:killsBy
|
antibody-dependent cellular cytotoxicity
apoptosis induction
|
|
gptkbp:marking
|
gptkb:CD56
gptkb:NKp30
gptkb:NKp44
gptkb:NKp46
CD16
|
|
gptkbp:partOf
|
innate immune system
|
|
gptkbp:proportionOfLymphocytes
|
5-20% in peripheral blood
|
|
gptkbp:recipient
|
gptkb:NKG2D
gptkb:CD94/NKG2
gptkb:KIR_(Killer-cell_Immunoglobulin-like_Receptor)
|
|
gptkbp:recognizedBy
|
cells with low MHC I
|
|
gptkbp:regulates
|
activating receptors
inhibitory receptors
|
|
gptkbp:relatedTo
|
gptkb:cell_surface_receptor
gptkb:B_cell
|
|
gptkbp:releaseYear
|
gptkb:interferon-gamma
gptkb:granzymes
gptkb:perforin
|
|
gptkbp:role
|
gptkb:immunotherapy
cancer immunology
viral infection response
|
|
gptkbp:species
|
gptkb:human
gptkb:mouse
other mammals
|
|
gptkbp:bfsParent
|
gptkb:NK
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Natural Killer cell
|