|
gptkbp:instanceOf
|
gptkb:protein
cytokine
|
|
gptkbp:approvalYear
|
1992
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:category
|
cytokine
immune system protein
|
|
gptkbp:discoveredBy
|
gptkb:Tadahiko_Uchiyama
gptkb:Takeshi_Uchiyama
|
|
gptkbp:discoveredIn
|
1976
|
|
gptkbp:Ensembl_ID
|
ENSG00000109471
|
|
gptkbp:function
|
stimulates growth of B cells
stimulates growth of T cells
stimulates growth of natural killer cells
|
|
gptkbp:gene
|
gptkb:IL2
|
|
gptkbp:GeneCards_ID
|
gptkb:IL2
|
|
gptkbp:HGNC_ID
|
6001
|
|
gptkbp:homologInRat
|
gptkb:Il2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
interleukin-2
|
|
gptkbp:locatedOnChromosome
|
gptkb:4q27
|
|
gptkbp:molecularWeight
|
15.5 kDa
|
|
gptkbp:OMIM
|
147680
|
|
gptkbp:orthologInMouse
|
gptkb:Il2
|
|
gptkbp:PDB
|
gptkb:1M47
|
|
gptkbp:producedBy
|
activated T cells
|
|
gptkbp:promotion
|
lymphocyte proliferation
|
|
gptkbp:recipient
|
gptkb:interleukin-2_receptor
|
|
gptkbp:regulates
|
immune response
|
|
gptkbp:sequence
|
153 amino acids
|
|
gptkbp:structure
|
four alpha-helix bundle
|
|
gptkbp:symbol
|
gptkb:IL-2
|
|
gptkbp:UniProtID
|
gptkb:P60568
|
|
gptkbp:usedAsDrug
|
gptkb:aldesleukin
|
|
gptkbp:usedForTreatmentOf
|
renal cell carcinoma
metastatic melanoma
|
|
gptkbp:bfsParent
|
gptkb:Cytokine-induced_killer_cell
gptkb:cell_surface_receptor
gptkb:CD4+_T_cells
|
|
gptkbp:bfsLayer
|
6
|