Statements (63)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:vaccine
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:IL-2_M
gptkb:IL-2_M3 |
| gptkbp:appointed_by |
high-dose therapy
|
| gptkbp:associated_with |
autoimmune diseases
|
| gptkbp:discovered_by |
1970s
|
| gptkbp:enhances |
antigen presentation
B cell growth |
| gptkbp:established |
apoptosis of T cells
|
| gptkbp:form |
IL-2a, IL-2b, IL-2c
|
| gptkbp:function |
stimulates T cell proliferation
|
| gptkbp:has_impact_on |
immune tolerance
|
| https://www.w3.org/2000/01/rdf-schema#label |
interleukin-2
|
| gptkbp:increased |
C D8+ T cell activity
natural killer cell activity |
| gptkbp:influences |
cytokine production
|
| gptkbp:is_aimed_at |
anti-IL-2 therapies
|
| gptkbp:is_associated_with |
chronic infections
|
| gptkbp:is_involved_in |
gptkb:asthma
gptkb:healthcare_organization gptkb:Crohn's_disease gptkb:systemic_lupus_erythematosus gptkb:ulcerative_colitis gptkb:psychologist gptkb:rheumatoid_arthritis COVID-19 response immune response allergic reactions neuroinflammation sepsis tumor microenvironment psoriasis chronic inflammation viral infections transplant rejection vaccine response T cell differentiation cell-mediated immunity tumor immunity type 1 diabetes host defense HIV infection immune surveillance immune checkpoint regulation T cell exhaustion Treg cell development |
| gptkbp:is_linked_to |
cytokine storm
|
| gptkbp:is_part_of |
adaptive immunity
|
| gptkbp:is_used_for |
a biomarker
|
| gptkbp:is_used_in |
clinical trials
|
| gptkbp:is_vulnerable_to |
gptkb:IL-2_receptor
|
| gptkbp:produced_by |
gptkb:T_cells
dendritic cells lymph nodes NK cells response to antigen |
| gptkbp:regulates |
IL-2 receptor signaling
|
| gptkbp:research_areas |
gptkb:healthcare_organization
|
| gptkbp:role |
regulating immune system
|
| gptkbp:security_features |
activated T cells
|
| gptkbp:targets |
T lymphocytes
|
| gptkbp:used_in |
gptkb:vaccine
|