KIR (Killer-cell Immunoglobulin-like Receptor)

URI: https://gptkb.org/entity/KIR_(Killer-cell_Immunoglobulin-like_Receptor)
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:CD158
gptkbp:binds gptkb:MHC_class_I_molecules
gptkbp:discoveredIn 1990s
gptkbp:encodedBy gptkb:KIR_gene_cluster
gptkbp:expressedIn gptkb:natural_killer_cells
some T cells
gptkbp:foundIn humans
primates
gptkbp:function regulation of natural killer cell activity
gptkbp:hasActivatingType gptkb:KIR2DS1
gptkbp:hasInhibitoryType gptkb:KIR2DL1
gptkbp:hasPolymorphism true
https://www.w3.org/2000/01/rdf-schema#label KIR (Killer-cell Immunoglobulin-like Receptor)
gptkbp:involvedIn immune response
recognition of tumor cells
recognition of infected cells
gptkbp:locatedOn gptkb:chromosome_19q13.4
gptkbp:regulates cytokine production
cytotoxicity of NK cells
gptkbp:significance infectious diseases
transplantation
autoimmune diseases
cancer immunology
gptkbp:subspecies gptkb:KIR2DS1
gptkb:KIR2DL1
gptkb:KIR2DL2
gptkb:KIR2DL3
gptkb:KIR2DS2
gptkb:KIR3DL1
gptkb:KIR3DS1
gptkbp:bfsParent gptkb:Natural_Killer_cell
gptkbp:bfsLayer 7