Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:receptor_tyrosine_kinase
gptkb:protein |
| gptkbp:activatedBy |
cytotoxicity
cytokine production |
| gptkbp:alternativeName |
gptkb:Killer_cell_lectin-like_receptor_subfamily_K,_member_1
gptkb:CD314 |
| gptkbp:encodedBy |
gptkb:KLRK1_gene
|
| gptkbp:foundIn |
humans
mice |
| gptkbp:foundOnCellType |
gptkb:natural_killer_cells
gptkb:NKT_cells gptkb:gamma_delta_T_cells gptkb:CD8+_T_cells |
| gptkbp:function |
immune surveillance
recognition of stressed cells |
| https://www.w3.org/2000/01/rdf-schema#label |
NKG2D
|
| gptkbp:ligand |
gptkb:MICB
gptkb:RAET1E gptkb:RAET1G gptkb:ULBP1 gptkb:ULBP2 gptkb:ULBP3 gptkb:ULBP4 gptkb:MICA |
| gptkbp:locatedOnChromosome |
12p13.2
|
| gptkbp:role |
autoimmune diseases
viral infections cancer immunosurveillance |
| gptkbp:signalingAdaptor |
gptkb:DAP10
gptkb:DAP12 |
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:structure |
type II transmembrane protein
|
| gptkbp:bfsParent |
gptkb:Cytokine-induced_killer_cell
|
| gptkbp:bfsLayer |
6
|