|
gptkbp:instanceOf
|
white blood cell
lymphocyte
|
|
gptkbp:activatedBy
|
immune response
helper T cell
|
|
gptkbp:canBe
|
affinity maturation
class switch recombination
somatic hypermutation
malignant (B cell lymphoma)
|
|
gptkbp:developedBy
|
hematopoietic stem cell
|
|
gptkbp:discoveredBy
|
gptkb:Robert_Good
gptkb:Max_Cooper
|
|
gptkbp:expressedIn
|
gptkb:B_cell_receptor_(BCR)
|
|
gptkbp:firstDescribed
|
1965
|
|
gptkbp:foundIn
|
lymph nodes
spleen
bone marrow
|
|
gptkbp:function
|
mediate humoral immunity
produce antibodies
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
B cell
|
|
gptkbp:interactsWith
|
gptkb:T_cells
antigen-presenting cells
|
|
gptkbp:marking
|
gptkb:CD20
gptkb:CD22
gptkb:CD79a
gptkb:CD79b
gptkb:CD19
gptkb:CD21
|
|
gptkbp:maturation
|
bone marrow
|
|
gptkbp:namedAfter
|
gptkb:bursa_of_Fabricius
|
|
gptkbp:presentIn
|
vertebrates
|
|
gptkbp:produces
|
gptkb:immunoglobulin_A_(IgA)
gptkb:immunoglobulin_D_(IgD)
gptkb:immunoglobulin_G_(IgG)
gptkb:immunoglobulin_M_(IgM)
gptkb:immunoglobulin_E_(IgE)
|
|
gptkbp:relatedTo
|
gptkb:dendritic_cell
cell surface receptor
natural killer cell
|
|
gptkbp:role
|
gptkb:adaptive_immune_system
autoimmune diseases
allergic reactions
vaccine response
|
|
gptkbp:subspecies
|
follicular B cell
marginal zone B cell
memory B cell
plasma cell
regulatory B cell
|
|
gptkbp:target
|
gptkb:rituximab
gptkb:ofatumumab
gptkb:obinutuzumab
|
|
gptkbp:bfsParent
|
gptkb:cell_surface_receptor
gptkb:APC
gptkb:adaptive_immune_system
gptkb:primary_mediastinal_large_B-cell_lymphoma
gptkb:primary_effusion_lymphoma
|
|
gptkbp:bfsLayer
|
6
|