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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alsoKnownAs
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gptkb:Natural_cytotoxicity_triggering_receptor_3
gptkb:NCR3
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gptkbp:alternativeSplicing
|
produces multiple isoforms
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gptkbp:associatedWith
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viral infection response
tumor cell recognition
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gptkbp:cellularComponent
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gptkb:cell_membrane
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gptkbp:discoveredBy
|
late 1990s
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gptkbp:encodedBy
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gptkb:NCR3_gene
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gptkbp:Entrez_Gene_ID
|
259197
|
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gptkbp:expressedIn
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gptkb:natural_killer_cells
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gptkbp:foundIn
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gptkb:Homo_sapiens
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gptkbp:function
|
activating receptor on natural killer cells
mediates cytotoxicity of NK cells
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gptkbp:GO_term
|
gptkb:GO:0001772_(natural_killer_cell_mediated_immunity)
gptkb:GO:0045087_(innate_immune_response)
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|
https://www.w3.org/2000/01/rdf-schema#label
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NKp30
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gptkbp:interactsWith
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gptkb:B7-H6
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gptkbp:ligand
|
gptkb:BAT3
gptkb:B7-H6
|
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gptkbp:locatedOnChromosome
|
chromosome 6p21.3
|
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gptkbp:molecularWeight
|
~30 kDa
|
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gptkbp:proteinFamily
|
gptkb:immunoglobulin_superfamily
|
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gptkbp:role
|
innate immune response
|
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gptkbp:structure
|
type I transmembrane protein
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gptkbp:UniProtID
|
gptkb:O14931
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gptkbp:bfsParent
|
gptkb:Natural_Killer_cell
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gptkbp:bfsLayer
|
7
|