Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cytokine
|
| gptkbp:alsoKnownAs |
gptkb:IL-18
|
| gptkbp:category |
gptkb:protein
cytokine immune system molecule |
| gptkbp:discoveredBy |
gptkb:Tetsuji_Okamura
|
| gptkbp:discoveredIn |
1995
|
| gptkbp:encodedBy |
gptkb:IL18_gene
|
| gptkbp:function |
enhances natural killer cell activity
induces interferon-gamma production promotes Th1 immune response |
| https://www.w3.org/2000/01/rdf-schema#label |
interleukin-18
|
| gptkbp:involvedIn |
gptkb:cancer
infectious diseases autoimmune diseases inflammatory response |
| gptkbp:location |
chromosome 11
|
| gptkbp:molecularWeight |
18 kDa
|
| gptkbp:PDB |
3WO2
|
| gptkbp:producedBy |
dendritic cells
macrophages |
| gptkbp:promotion |
IFN-gamma production
|
| gptkbp:recipient |
gptkb:IL-18_receptor
|
| gptkbp:regulates |
immune response
|
| gptkbp:structure |
pro-inflammatory protein
|
| gptkbp:UniProtID |
gptkb:Q14116
|
| gptkbp:bfsParent |
gptkb:Natural_Killer_cell
gptkb:Th1_immune_response |
| gptkbp:bfsLayer |
7
|