Mitogen-activated protein kinase 3

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:enzyme
gptkbp:alsoKnownAs	gptkb:ERK1 gptkb:Extracellular_signal-regulated_kinase_1
gptkbp:biologicalProcess	cell proliferation differentiation MAPK cascade protein serine/threonine kinase activity transcription regulation
gptkbp:cellularComponent	gptkb:nucleus gptkb:cytoplasm
gptkbp:enzymeCommissionNumber	2.7.11.24
gptkbp:expressedIn	many tissues
gptkbp:gene	gptkb:MAPK3
gptkbp:gene_id_(NCBI)	5595
gptkbp:interactsWith	gptkb:MAPK1 gptkb:ELK1 gptkb:JUN gptkb:FOS gptkb:MYC gptkb:RSK1
gptkbp:involved_in_disease	gptkb:cancer gptkb:Noonan_syndrome neurodevelopmental disorders
gptkbp:length	379
gptkbp:locatedIn	gptkb:Homo_sapiens
gptkbp:locatedOnChromosome	gptkb:16p11.2
gptkbp:molecularWeight	43 kDa
gptkbp:orthologInMouse	gptkb:Mapk3
gptkbp:part_of_pathway	gptkb:MAPK/ERK_pathway
gptkbp:pdb_id	2ZOQ 4QTB
gptkbp:phosphorylates	gptkb:MAP2K1 gptkb:MAP2K2
gptkbp:product	gptkb:MAPK3
gptkbp:refseq_mRNA	NM_002745.4
gptkbp:refseq_protein	NP_002736.3
gptkbp:regulates	apoptosis cell differentiation gene expression cell migration cell cycle
gptkbp:substrate	gptkb:MAP2K1 gptkb:MAP2K2
gptkbp:UniProtID	gptkb:P27361
gptkbp:bfsParent	gptkb:ERK1 gptkb:MAPK3 gptkb:MAPK3_gene
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Mitogen-activated protein kinase 3