|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:activatedBy
|
gptkb:MAPK/ERK_pathway
|
|
gptkbp:alias
|
gptkb:ELK-1
gptkb:ETS_domain-containing_protein_Elk-1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:binds
|
gptkb:serum_response_element_(SRE)
|
|
gptkbp:discoveredBy
|
gptkb:Richard_Treisman
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:encodedBy
|
gptkb:ELK1_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000198901
2002
|
|
gptkbp:expressedIn
|
gptkb:testis
brain
heart
liver
|
|
gptkbp:fullName
|
gptkb:ETS_domain-containing_protein_Elk-1
|
|
gptkbp:function
|
transcription factor
regulation of gene expression
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
3321
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ELK1
|
|
gptkbp:interactsWith
|
gptkb:CBP/p300
gptkb:MED23
gptkb:SRF_(serum_response_factor)
|
|
gptkbp:length
|
428 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:Xq12
X
|
|
gptkbp:memberOf
|
gptkb:ETS_transcription_factor_family
|
|
gptkbp:molecularWeight
|
48 kDa
|
|
gptkbp:OMIM
|
311040
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:phosphorylates
|
gptkb:ERK1
gptkb:ERK2
gptkb:JNK
gptkb:p38_MAPK
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
acetylation
|
|
gptkbp:regulates
|
gptkb:EGR1
gptkb:c-Fos
gptkb:JUNB
immediate early genes
|
|
gptkbp:relatedTo
|
gptkb:cancer
apoptosis
cell proliferation
neuronal differentiation
|
|
gptkbp:structure
|
contains B-box domain
contains ETS DNA-binding domain
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
gptkb:P19419
|
|
gptkbp:bfsParent
|
gptkb:p38_MAPK_pathway
|
|
gptkbp:bfsLayer
|
6
|