Statements (67)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:alias |
gelatinase A
|
| gptkbp:associated_with |
extracellular matrix remodeling
|
| gptkbp:code |
matrix metalloproteinase-2
|
| gptkbp:discovered_by |
1990s
|
| gptkbp:genetic_studies |
disease susceptibility
|
| gptkbp:has_function |
degrading collagen
|
| gptkbp:has_role |
angiogenesis
|
| https://www.w3.org/2000/01/rdf-schema#label |
MMP2 gene
|
| gptkbp:interacts_with |
MMP inhibitors
|
| gptkbp:involved_in |
wound healing
|
| gptkbp:is_associated_with |
gptkb:neurodegenerative_diseases
pulmonary diseases diabetes complications |
| gptkbp:is_expressed_in |
muscle tissue
placenta various tissues adipose tissue embryogenesis brain tissue cancer cells fibroblasts endothelial cells skin cells smooth muscle cells |
| gptkbp:is_involved_in |
cell differentiation
cell proliferation immune response metabolic disorders inflammation fibrosis cell signaling pathways tumor microenvironment vascular remodeling tissue repair cell migration tissue remodeling cancer metastasis tumor invasion neoplastic processes angiogenic processes |
| gptkbp:is_linked_to |
age-related diseases
liver diseases chronic diseases metabolic syndrome chronic kidney disease chronic inflammation metastasis chronic pain conditions obesity-related conditions |
| gptkbp:is_part_of |
MMP family
proteolytic cascade |
| gptkbp:is_regulated_by |
growth factors
transcription factors hormones micro RNAs |
| gptkbp:is_studied_for |
therapeutic interventions
biomarker potential |
| gptkbp:is_studied_in |
autoimmune diseases
cardiovascular diseases infectious diseases |
| gptkbp:is_targeted_at |
therapeutic agents
|
| gptkbp:located_in |
gptkb:human_chromosome_16
|
| gptkbp:orthologs |
other species
|
| gptkbp:related_to |
cancer progression
|
| gptkbp:bfsParent |
gptkb:MMP2
|
| gptkbp:bfsLayer |
8
|