Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
collagen |
| gptkbp:component |
glomerular basement membrane
lens capsule muscle basement membrane |
| gptkbp:discoveredBy |
gptkb:Kefalides_NA
|
| gptkbp:encodedBy |
gptkb:COL4A2
gptkb:COL4A1 COL4A5 COL4A3 COL4A4 COL4A6 |
| gptkbp:features |
forms sheet-like networks
contains interruptions in Gly-X-Y repeats |
| gptkbp:form |
network-like structure
|
| gptkbp:foundIn |
basement membrane
|
| gptkbp:function |
structural support
|
| https://www.w3.org/2000/01/rdf-schema#label |
collagen type IV
|
| gptkbp:molecularWeight |
~400 kDa (trimer)
|
| gptkbp:mutationAssociatedWith |
gptkb:Alport_syndrome
gptkb:Goodpasture_syndrome |
| gptkbp:presentIn |
all vertebrates
|
| gptkbp:role |
filtration barrier in kidney
tissue compartmentalization |
| gptkbp:subunit |
gptkb:alpha-1(IV)_chain
gptkb:alpha-2(IV)_chain gptkb:alpha-3(IV)_chain gptkb:alpha-4(IV)_chain gptkb:alpha-5(IV)_chain gptkb:alpha-6(IV)_chain |
| gptkbp:bfsParent |
gptkb:DDR1
gptkb:MMP9 |
| gptkbp:bfsLayer |
7
|