Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
activated by proteolytic cleavage
secreted as proenzyme |
| gptkbp:alsoKnownAs |
gptkb:MMP-2
matrix metalloproteinase-2 |
| gptkbp:cofactor |
zinc
calcium |
| gptkbp:EC_number |
3.4.24.24
|
| gptkbp:family |
gptkb:matrix_metalloproteinase
|
| gptkbp:function |
degrades gelatin
degrades type IV collagen |
| gptkbp:gene |
gptkb:MMP2
|
| https://www.w3.org/2000/01/rdf-schema#label |
gelatinase A
|
| gptkbp:inhibitedBy |
TIMP-1
TIMP-2 |
| gptkbp:locatedOnChromosome |
16q13-q21
|
| gptkbp:location |
extracellular matrix
|
| gptkbp:molecularWeight |
72 kDa
|
| gptkbp:OMIM |
120360
|
| gptkbp:organism |
gptkb:human
|
| gptkbp:role |
angiogenesis
metastasis tissue remodeling tumor invasion |
| gptkbp:structure |
contains fibronectin type II-like repeats
|
| gptkbp:substrate |
gptkb:fibronectin
gptkb:elastin gptkb:type_IV_collagen gelatin |
| gptkbp:UniProtID |
P08253
|
| gptkbp:bfsParent |
gptkb:Fibronectin_type_II_domain
gptkb:MMP2 |
| gptkbp:bfsLayer |
7
|