Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
large external transformation-sensitive protein (LETS protein)
|
| gptkbp:alternativeSplicing |
produces multiple isoforms
|
| gptkbp:binds |
gptkb:integrins
gptkb:heparin gptkb:fibrin collagen |
| gptkbp:degradedBy |
proteases
|
| gptkbp:discoveredBy |
gptkb:Ludwig_Aschoff
|
| gptkbp:domain |
contains type I, II, and III repeats
|
| gptkbp:encodedBy |
FN1 gene
|
| gptkbp:firstDescribed |
1948
|
| gptkbp:foundIn |
blood plasma
extracellular matrix |
| gptkbp:function |
wound healing
cell migration cell adhesion tissue repair |
| https://www.w3.org/2000/01/rdf-schema#label |
fibronectin
|
| gptkbp:interactsWith |
gptkb:matrix_metalloproteinases
growth factors |
| gptkbp:medicalUse |
wound healing therapies
biomarker for tissue injury |
| gptkbp:molecularWeight |
~440 kDa
|
| gptkbp:presentIn |
vertebrates
|
| gptkbp:role |
angiogenesis
metastasis embryogenesis |
| gptkbp:structure |
dimer
|
| gptkbp:subunit |
two nearly identical polypeptide chains
|
| gptkbp:bfsParent |
gptkb:CD61
gptkb:FN2 |
| gptkbp:bfsLayer |
6
|