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gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
large external transformation-sensitive protein (LETS protein)
|
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gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:binds
|
gptkb:integrins
gptkb:collagen
gptkb:heparin
gptkb:fibrin
|
|
gptkbp:degradedBy
|
proteases
|
|
gptkbp:discoveredBy
|
gptkb:Ludwig_Aschoff
|
|
gptkbp:domain
|
contains type I, II, and III repeats
|
|
gptkbp:encodedBy
|
FN1 gene
|
|
gptkbp:firstDescribed
|
1948
|
|
gptkbp:foundIn
|
gptkb:extracellular_matrix
blood plasma
|
|
gptkbp:function
|
wound healing
cell migration
cell adhesion
tissue repair
|
|
gptkbp:interactsWith
|
gptkb:matrix_metalloproteinases
growth factors
|
|
gptkbp:medicalUse
|
wound healing therapies
biomarker for tissue injury
|
|
gptkbp:molecularWeight
|
~440 kDa
|
|
gptkbp:presentIn
|
vertebrates
|
|
gptkbp:role
|
angiogenesis
metastasis
embryogenesis
|
|
gptkbp:structure
|
dimer
|
|
gptkbp:subunit
|
two nearly identical polypeptide chains
|
|
gptkbp:bfsParent
|
gptkb:Fetal_Bovine_Serum
gptkb:Extracellular_Matrix
gptkb:CD61
gptkb:FN2
gptkb:MMP2
gptkb:MMP3
gptkb:MMP7
gptkb:MMP9
gptkb:alpha-4_beta-1_integrin
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
fibronectin
|