|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
tropoelastin (precursor form)
|
|
gptkbp:aminoAcidComposition
|
rich in glycine, valine, alanine, proline
|
|
gptkbp:associatedWith
|
gptkb:cutis_laxa
gptkb:Williams_syndrome
supravalvular aortic stenosis
|
|
gptkbp:color
|
yellowish
|
|
gptkbp:crosslinkedBy
|
lysyl oxidase
|
|
gptkbp:degradedBy
|
gptkb:elastase
|
|
gptkbp:discoveredBy
|
Nicolet and Scott
|
|
gptkbp:encodedBy
|
ELN gene
|
|
gptkbp:firstDescribed
|
1877
|
|
gptkbp:foundIn
|
gptkb:skin
gptkb:skeletal_muscle
lungs
bladder
arteries
elastic ligaments
|
|
gptkbp:function
|
provides elasticity
|
|
gptkbp:majorComponentOf
|
elastic fibers
|
|
gptkbp:molecularWeight
|
about 72 kDa
|
|
gptkbp:resistantTo
|
proteolytic enzymes
|
|
gptkbp:role
|
blood vessel elasticity
tissue recoil
|
|
gptkbp:solubility
|
insoluble in water
|
|
gptkbp:structure
|
highly hydrophobic
random coil conformation
|
|
gptkbp:synthesisType
|
fibroblasts
smooth muscle cells
|
|
gptkbp:turnoverRate
|
very low in adults
|
|
gptkbp:bfsParent
|
gptkb:elastase
gptkb:Extracellular_Matrix
gptkb:MMP2
gptkb:MMP7
gptkb:MMP9
gptkb:Matrix_metalloproteinase
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
elastin
|