elastin

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName tropoelastin (precursor form)
gptkbp:aminoAcidComposition rich in glycine, valine, alanine, proline
gptkbp:associatedWith gptkb:cutis_laxa
gptkb:Williams_syndrome
supravalvular aortic stenosis
gptkbp:color yellowish
gptkbp:crosslinkedBy lysyl oxidase
gptkbp:degradedBy gptkb:elastase
gptkbp:discoveredBy Nicolet and Scott
gptkbp:encodedBy ELN gene
gptkbp:firstDescribed 1877
gptkbp:foundIn gptkb:skin
gptkb:skeletal_muscle
lungs
bladder
arteries
elastic ligaments
gptkbp:function provides elasticity
https://www.w3.org/2000/01/rdf-schema#label elastin
gptkbp:majorComponentOf elastic fibers
gptkbp:molecularWeight about 72 kDa
gptkbp:resistantTo proteolytic enzymes
gptkbp:role blood vessel elasticity
tissue recoil
gptkbp:solubility insoluble in water
gptkbp:structure highly hydrophobic
random coil conformation
gptkbp:synthesisType fibroblasts
smooth muscle cells
gptkbp:turnoverRate very low in adults
gptkbp:bfsParent gptkb:Sulfolobus_acidocaldarius
gptkbp:bfsLayer 6