|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
gptkb:epidermolysis_bullosa
muscular dystrophy
cancer metastasis
|
|
gptkbp:composedOf
|
alpha chain
beta chain
gamma chain
|
|
gptkbp:discoveredBy
|
gptkb:Ruud_A._Sonnenberg
|
|
gptkbp:encodedBy
|
gptkb:LAMA_genes
gptkb:LAMB_genes
gptkb:LAMC_genes
|
|
gptkbp:firstDescribed
|
1979
|
|
gptkbp:form
|
cross-shaped structure
|
|
gptkbp:foundIn
|
extracellular matrix
|
|
gptkbp:function
|
cell differentiation
cell migration
cell signaling
cell adhesion
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
laminin
|
|
gptkbp:interactsWith
|
gptkb:heparan_sulfate_proteoglycans
gptkb:integrins
gptkb:dystroglycan
|
|
gptkbp:molecularWeight
|
400-900 kDa
|
|
gptkbp:presentIn
|
invertebrates
vertebrates
basement membrane
all animals
|
|
gptkbp:proteinFamily
|
gptkb:laminin_gene_family
|
|
gptkbp:role
|
wound healing
angiogenesis
neural development
tissue development
|
|
gptkbp:structure
|
heterotrimer
|
|
gptkbp:subunit
|
gptkb:LAMB3
gptkb:LAMA3
gptkb:LAMA5
gptkb:LAMB1
gptkb:LAMB2
gptkb:LAMC1
gptkb:LAMC2
gptkb:LAMC3
gptkb:LAMA1
gptkb:LAMA2
gptkb:LAMA4
|
|
gptkbp:usedIn
|
biomedical research
tissue engineering
cell culture substrates
|
|
gptkbp:bfsParent
|
gptkb:Nidogen_(protein_family)
|
|
gptkbp:bfsLayer
|
6
|