|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:abbreviation
|
gptkb:Mitogen-activated_protein_kinase_kinase
|
|
gptkbp:activatedBy
|
gptkb:MAP_kinase_kinase_kinase_(MAP3K)
|
|
gptkbp:alternativeName
|
gptkb:MEK
|
|
gptkbp:catalyzes
|
phosphorylation of MAPK
|
|
gptkbp:enzymeCommissionNumber
|
2.7.12.2
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:fullName
|
gptkb:Mitogen-activated_protein_kinase_kinase
|
|
gptkbp:function
|
phosphorylates MAP kinases
|
|
gptkbp:hasIsoform
|
gptkb:MKK3
gptkb:MKK4
gptkb:MKK6
gptkb:MKK7
gptkb:MKK5
gptkb:MKK1
gptkb:MKK2
|
|
gptkbp:involvedIn
|
gptkb:MAPK_signaling_pathway
|
|
gptkbp:proteinFamily
|
gptkb:MAP2K
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
stress response
|
|
gptkbp:relatedTo
|
gptkb:ERK_pathway
gptkb:JNK_pathway
gptkb:p38_MAPK_pathway
|
|
gptkbp:target
|
pharmaceutical inhibitors (e.g., MEK inhibitors)
|
|
gptkbp:bfsParent
|
gptkb:Main-Kinzig-Kreis
gptkb:Erlensee
gptkb:MAPK_pathway
gptkb:Mitsubishi_Kakoki_Kaisha
gptkb:Hammersbach
gptkb:Sinntal
gptkb:Gelnhausen
gptkb:Maintal
gptkb:Schlüchtern
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MKK
|