|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:MAP2K3
gptkb:MAP_kinase_kinase_3
gptkb:MEK3
|
|
gptkbp:associatedWith
|
gptkb:cancer
inflammatory diseases
|
|
gptkbp:biologicalProcess
|
apoptotic process
inflammatory response
protein serine/threonine kinase activity
cellular response to stress
|
|
gptkbp:encodedBy
|
gptkb:MAP2K3_gene
|
|
gptkbp:Entrez_Gene_ID
|
5606
|
|
gptkbp:enzymeClassification
|
gptkb:EC_2.7.12.2
|
|
gptkbp:fullName
|
gptkb:Mitogen-activated_protein_kinase_kinase_3
|
|
gptkbp:function
|
phosphorylates and activates p38 MAP kinase
|
|
gptkbp:HGNC_ID
|
6847
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MKK3
|
|
gptkbp:locatedOnChromosome
|
17q11.2-q12
|
|
gptkbp:OMIM
|
603166
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
|
|
gptkbp:phosphorylates
|
gptkb:MAPK11
gptkb:MAPK12
gptkb:MAPK13
gptkb:MAPK14
|
|
gptkbp:regulates
|
activated by phosphorylation
activated by upstream kinases such as MAP3K
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P46734
|
|
gptkbp:bfsParent
|
gptkb:p38_MAPK_pathway
|
|
gptkbp:bfsLayer
|
6
|