MAP kinase kinase kinase (MAP3K)
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activity |
MAP kinase kinase kinase activity
|
| gptkbp:alsoKnownAs |
gptkb:MAP3K
|
| gptkbp:contains |
kinase domain
|
| gptkbp:downstreamOf |
gptkb:MAPK
gptkb:MAP2K |
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
neurodegenerative diseases inflammatory diseases |
| gptkbp:enzymeClassification |
serine/threonine protein kinase
|
| gptkbp:example |
gptkb:TAK1
gptkb:RAF gptkb:MEKK1 ASK1 |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
phosphorylates MAP kinase kinase (MAP2K)
|
| gptkbp:GO_term |
GO:0004709
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAP kinase kinase kinase (MAP3K)
|
| gptkbp:involvedIn |
gptkb:MAPK_signaling_pathway
|
| gptkbp:partOf |
signal transduction
|
| gptkbp:regulates |
cellular responses to cytokines
cellular responses to growth factors cellular responses to stress |
| gptkbp:bfsParent |
gptkb:MAP_kinase_kinase_(MAP2K)
gptkb:MAP_kinase_kinase_(MEK) gptkb:MKK gptkb:MAP_kinase_kinase |
| gptkbp:bfsLayer |
7
|