|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:MAP2K6
gptkb:MEK6
gptkb:PRKMK6
gptkb:SKK3
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
inflammatory diseases
|
|
gptkbp:biologicalProcess
|
apoptotic process
inflammatory response
protein serine/threonine kinase activity
cellular response to stress
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodedBy
|
gptkb:MAP2K6_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000108984
5608
|
|
gptkbp:enzymeCommissionNumber
|
2.7.12.2
|
|
gptkbp:fullName
|
gptkb:Mitogen-activated_protein_kinase_kinase_6
|
|
gptkbp:function
|
MAP kinase kinase activity
phosphorylates and activates p38 MAP kinase
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
6840
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MKK6
|
|
gptkbp:interactsWith
|
gptkb:TAK1
gptkb:MAP3K7
gptkb:TAB1
ASK1
|
|
gptkbp:length
|
334
|
|
gptkbp:locatedOnChromosome
|
17q24.3
|
|
gptkbp:molecularWeight
|
37.6 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse
right
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
|
|
gptkbp:PDB
|
2GHL
2OJG
3VUT
|
|
gptkbp:phosphorylates
|
gptkb:MAPK11
gptkb:MAPK12
gptkb:MAPK13
gptkb:MAPK14
Ser207
Thr211
|
|
gptkbp:RefSeq
|
gptkb:NM_002758
|
|
gptkbp:regulates
|
gptkb:p38_MAPK_pathway
|
|
gptkbp:species
|
gptkb:human
|
|
gptkbp:UniProtID
|
gptkb:P52564
|
|
gptkbp:bfsParent
|
gptkb:p38_MAPK_pathway
|
|
gptkbp:bfsLayer
|
6
|