|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
gptkb:graft-versus-host_disease
autoimmune disease
|
|
gptkbp:binds
|
peptide antigen
|
|
gptkbp:component
|
gptkb:beta-2_microglobulin
alpha chain
beta chain
|
|
gptkbp:discoveredIn
|
20th century
|
|
gptkbp:encodedBy
|
gptkb:MHC_gene
|
|
gptkbp:example
|
gptkb:HLA-A
gptkb:HLA-B
gptkb:HLA-DR
gptkb:H-2_(mouse)
|
|
gptkbp:foundIn
|
vertebrates
|
|
gptkbp:fullName
|
gptkb:Major_Histocompatibility_Complex_molecule
|
|
gptkbp:function
|
antigen presentation
|
|
gptkbp:hasPolymorphism
|
high
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MHC molecule
|
|
gptkbp:importantFor
|
self/non-self discrimination
|
|
gptkbp:location
|
cell surface
|
|
gptkbp:presentedBy
|
T lymphocyte
|
|
gptkbp:recognizedBy
|
gptkb:CD4+_T_cell
gptkb:CD8+_T_cell
cell surface receptor
|
|
gptkbp:role
|
immune response
transplant rejection
|
|
gptkbp:species
|
high
|
|
gptkbp:structure
|
heterodimer
|
|
gptkbp:studiedIn
|
immunology
|
|
gptkbp:type
|
gptkb:MHC_class_II
gptkb:MHC_class_I
gptkb:MHC_class_III
|
|
gptkbp:bfsParent
|
gptkb:immune_response
|
|
gptkbp:bfsLayer
|
5
|