immunological synapse

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf Cell
gptkbp:composedOf central supramolecular activation cluster
distal supramolecular activation cluster
peripheral supramolecular activation cluster
gptkbp:discoveredBy gptkb:Michael_Dustin
gptkbp:enables T cell activation
antigen recognition
cytokine release
directed secretion
lytic granule delivery
gptkbp:firstDescribed 1999
gptkbp:foundIn immune system
gptkbp:function signal transduction
cell-cell communication
https://www.w3.org/2000/01/rdf-schema#label immunological synapse
gptkbp:involves cell surface receptor
antigen-presenting cell
gptkbp:involvesMolecules gptkb:ICAM-1
gptkb:CD28
gptkb:CD3
gptkb:LFA-1
gptkb:MHC_molecule
cell surface receptor
gptkbp:relatedTo immune response
B cell activation
adaptive immunity
cytotoxic T cell
helper T cell
gptkbp:studiedIn immunology
gptkbp:synonym gptkb:immune_synapse
gptkbp:bfsParent gptkb:T-cell_receptor_complex
gptkb:PKC_theta
gptkbp:bfsLayer 7