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gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
Human leukocyte antigen B
HLA class I histocompatibility antigen, B alpha chain
|
|
gptkbp:associatedWith
|
ankylosing spondylitis
abacavir hypersensitivity
carbamazepine-induced Stevens-Johnson syndrome
|
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gptkbp:biologicalProcess
|
adaptive immune response
peptide antigen binding
|
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gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
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gptkbp:discoveredIn
|
1960s
|
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gptkbp:encodes
|
HLA-B protein
|
|
gptkbp:Entrez_Gene_ID
|
3106
rs1050450
rs1050451
rs1131500
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
lymphocytes
|
|
gptkbp:foundIn
|
humans
|
|
gptkbp:function
|
presents peptide antigens to T cells
|
|
gptkbp:hasAllele
|
HLA-B*15:02
HLA-B*27
HLA-B*57
HLA-B*58:01
|
|
gptkbp:hasIsoform
|
gptkb:HLA-B27
HLA-B15
HLA-B57
|
|
gptkbp:hasPolymorphism
|
high
|
|
gptkbp:hasRole
|
immune system
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:4933
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HLA-B
|
|
gptkbp:involvedIn
|
antigen presentation
|
|
gptkbp:locatedOn
|
gptkb:chromosome_6
|
|
gptkbp:OMIM
|
142830
|
|
gptkbp:orthologIn
|
gptkb:lion
|
|
gptkbp:partOf
|
gptkb:major_histocompatibility_complex
|
|
gptkbp:proteinFamily
|
gptkb:MHC_class_I
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:significance
|
organ transplantation
adverse drug reactions
autoimmune disease susceptibility
|
|
gptkbp:UniProtID
|
P01889
|
|
gptkbp:bfsParent
|
gptkb:MHC_molecule
|
|
gptkbp:bfsLayer
|
6
|