graft-versus-host disease

GPTKB entity

Statements (47)
Predicate Object
gptkbp:instanceOf gptkb:disease
immune system disorder
gptkbp:affects gptkb:skin
lungs
gastrointestinal tract
liver
eyes
mouth
recipients of bone marrow transplant
recipients of stem cell transplant
gptkbp:alsoKnownAs gptkb:GVHD
gptkbp:causedBy allogeneic tissue transplant
gptkbp:complication hematopoietic stem cell transplantation
gptkbp:diagnosedBy laboratory tests
clinical evaluation
biopsy
gptkbp:field immunology
hematology
gptkbp:firstDescribed 1950s
https://www.w3.org/2000/01/rdf-schema#label graft-versus-host disease
gptkbp:ICD-10_code T86.0
gptkbp:MeSH_ID D006111
gptkbp:OMIM 611194
gptkbp:prevention HLA matching
immunosuppressive prophylaxis
gptkbp:riskFactor gptkb:HLA_mismatch
female donor to male recipient
older donor age
gptkbp:subspecies gptkb:acute_graft-versus-host_disease
gptkb:chronic_graft-versus-host_disease
gptkbp:symptom nausea
vomiting
diarrhea
abdominal pain
fatigue
jaundice
weight loss
skin rash
dry mouth
liver dysfunction
gptkbp:treatment gptkb:antithymocyte_globulin
immunosuppressive therapy
corticosteroids
calcineurin inhibitors
extracorporeal photopheresis
gptkbp:bfsParent gptkb:Jakavi
gptkbp:bfsLayer 5