MHC gene

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:associatedWith autoimmune diseases
organ transplant compatibility
gptkbp:discoveredIn 1970s
gptkbp:encodes MHC protein
gptkbp:expressedIn immune cells
gptkbp:foundIn vertebrates
gptkbp:fullName Major Histocompatibility Complex gene
gptkbp:function immune system regulation
antigen presentation
gptkbp:hasPolymorphism true
https://www.w3.org/2000/01/rdf-schema#label MHC gene
gptkbp:locatedOn chromosome 6 (in humans)
gptkbp:mayInclude gptkb:Class_I
gptkb:Class_II
gptkb:Class_III
gptkbp:orthologousIn gptkb:mouse_(H-2_complex)
gptkbp:relatedTo T cell activation
antigen processing
peptide binding
HLA gene (in humans)
gptkbp:bfsParent gptkb:MHC_molecule
gptkbp:bfsLayer 6