|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:associatedWith
|
infectious diseases
autoimmune diseases
cancer immunology
organ transplantation compatibility
|
|
gptkbp:biologicalProcess
|
antigen processing and presentation
MHC class I receptor activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
gptkb:Jean_Dausset
|
|
gptkbp:discoveredIn
|
1958
|
|
gptkbp:encodes
|
HLA class I histocompatibility antigen, A alpha chain
|
|
gptkbp:Entrez_Gene_ID
|
3105
ENSG00000206503
|
|
gptkbp:expressedIn
|
most nucleated cells
|
|
gptkbp:function
|
presents peptide antigens to the immune system
|
|
gptkbp:geneType
|
protein coding
|
|
gptkbp:hasAllele
|
HLA-A*01:01
HLA-A*02:01
HLA-A*03:01
HLA-A*11:01
HLA-A*23:01
HLA-A*24:02
HLA-A*25:01
HLA-A*26:01
HLA-A*31:01
HLA-A*32:01
HLA-A*33:01
HLA-A*34:01
HLA-A*36:01
HLA-A*66:01
HLA-A*68:01
HLA-A*69:01
HLA-A*74:01
HLA-A*80:01
|
|
gptkbp:hasPseudogene
|
HLA-A pseudogene
|
|
gptkbp:hasTranscript
|
NM_002116
|
|
gptkbp:HGNC_ID
|
HGNC:4931
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HLA-A
|
|
gptkbp:isPolymorphic
|
true
|
|
gptkbp:length
|
365 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:locusType
|
gptkb:6p21.3
|
|
gptkbp:molecularWeight
|
40-45 kDa
|
|
gptkbp:OMIM
|
142800
|
|
gptkbp:orthologInMouse
|
H2-K
|
|
gptkbp:partOf
|
gptkb:HLA_complex
gptkb:major_histocompatibility_complex
|
|
gptkbp:product
|
NP_002107
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:symbol
|
gptkb:HLA-A
|
|
gptkbp:UniProtID
|
P01892
|
|
gptkbp:bfsParent
|
gptkb:MHC_molecule
|
|
gptkbp:bfsLayer
|
6
|