Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:B2M
β2-microglobulin |
| gptkbp:associatedWith |
dialysis-related amyloidosis
|
| gptkbp:component |
gptkb:MHC_class_I_molecules
|
| gptkbp:discoveredIn |
1960s
|
| gptkbp:encodedBy |
B2M gene
|
| gptkbp:excretion |
kidneys
|
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
immune system regulation
antigen presentation |
| gptkbp:halfLife |
2-4 hours
|
| https://www.w3.org/2000/01/rdf-schema#label |
beta-2 microglobulin
|
| gptkbp:locatedOnChromosome |
15q21-q22
|
| gptkbp:location |
blood plasma
cell surface |
| gptkbp:molecularWeight |
11.8 kDa
|
| gptkbp:OMIM |
109700
|
| gptkbp:PDB |
1LDS
|
| gptkbp:significance |
elevated in chronic kidney disease
elevated in multiple myeloma elevated in some lymphomas marker for renal function |
| gptkbp:structure |
single polypeptide chain
|
| gptkbp:UniProtID |
P61769
|
| gptkbp:bfsParent |
gptkb:small_lymphocytic_lymphoma
gptkb:MHC_molecule |
| gptkbp:bfsLayer |
6
|