|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:MKK6
gptkb:MEK6
gptkb:PRKMK6
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
inflammatory diseases
|
|
gptkbp:biologicalProcess
|
signal transduction
protein serine/threonine kinase activity
cellular response to stress
|
|
gptkbp:discoveredBy
|
1996
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000108984
5608
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
gptkb:Mitogen-activated_protein_kinase_kinase_6
|
|
gptkbp:function
|
phosphorylates and activates p38 MAP kinase
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:MAP2K6
|
|
gptkbp:interactsWith
|
gptkb:MAPK11
gptkb:MAPK12
gptkb:MAPK13
gptkb:MAPK14
|
|
gptkbp:length
|
334
|
|
gptkbp:locatedOnChromosome
|
17
17q24.3
|
|
gptkbp:molecularWeight
|
37.6 kDa
|
|
gptkbp:OMIM
|
602425
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Map2k6
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
stress-activated protein kinase pathway
|
|
gptkbp:PDB
|
gptkb:2FYN
4QTB
3VUT
|
|
gptkbp:phosphorylates
|
gptkb:TAK1
gptkb:MAP3K6
gptkb:MAP3K7
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell cycle arrest
inflammatory response
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P52564
|
|
gptkbp:bfsParent
|
gptkb:p38_MAPK_pathway
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAP2K6
|