|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:ERBB
gptkb:ERBB1
gptkb:HER1
mENA
|
|
gptkbp:approvalYear
|
1986-03-10
|
|
gptkbp:approvedBy
|
gptkb:epidermal_growth_factor_receptor
|
|
gptkbp:approvedSymbol
|
gptkb:EGFR
|
|
gptkbp:associatedWith
|
gptkb:ERBB3
gptkb:cancer
gptkb:ERBB2
gptkb:glioblastoma
gptkb:ERBB4
gptkb:non-small_cell_lung_carcinoma
colorectal cancer
|
|
gptkbp:endPoint
|
55279321
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000146648
1956
|
|
gptkbp:function
|
receptor tyrosine kinase activity
epidermal growth factor binding
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3486
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HGNC:3486
|
|
gptkbp:locatedOnChromosome
|
gptkb:7p11.2
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:locusType
|
gene with protein product
|
|
gptkbp:OMIM
|
131550
|
|
gptkbp:orthologIn
|
chicken: EGFR
mouse: Egfr
rat: Egfr
zebrafish: egfra
|
|
gptkbp:previousSymbols
|
gptkb:ERBB
gptkb:ERBB1
gptkb:HER1
|
|
gptkbp:proteinFamily
|
protein tyrosine kinase
EGF receptor family
|
|
gptkbp:RefSeq
|
NM_005228
|
|
gptkbp:startPoint
|
55086714
|
|
gptkbp:strand
|
plus
|
|
gptkbp:symbol
|
approved
|
|
gptkbp:target
|
gptkb:afatinib
gptkb:cetuximab
gptkb:erlotinib
gptkb:gefitinib
gptkb:osimertinib
gptkb:necitumumab
gptkb:dacomitinib
gptkb:lapatinib
gptkb:panitumumab
|
|
gptkbp:UniProtID
|
gptkb:P00533
|
|
gptkbp:bfsParent
|
gptkb:ETV2
|
|
gptkbp:bfsLayer
|
8
|