non-small cell lung carcinoma

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:cancer
gptkbp:accountsFor	about 85% of lung cancers
gptkbp:diagnosedBy	imaging cytology biopsy
gptkbp:hasBiomarker	gptkb:ALK_rearrangement gptkb:EGFR_mutation gptkb:PD-L1_expression
gptkbp:hasCommonTreatment	surgery radiation therapy chemotherapy immunotherapy
gptkbp:hasFirstLineTherapy	platinum-based chemotherapy
gptkbp:hasGenderPrevalence	more common in males
gptkbp:hasICD-O-3Code	8046/3
gptkbp:hasMedianSurvival	less than 1 year (advanced stage)
gptkbp:hasMetastasisSite	gptkb:bone gptkb:adrenal_gland brain liver
gptkbp:hasScreeningMethod	gptkb:low-dose_CT_scan
gptkbp:hasTargetedTherapy	tyrosine kinase inhibitors immune checkpoint inhibitors
gptkbp:histology	large undifferentiated cells glandular (adenocarcinoma) keratinizing (squamous cell)
https://www.w3.org/2000/01/rdf-schema#label	non-small cell lung carcinoma
gptkbp:ICD-10_code	C34
gptkbp:isMostCommonLungCancerType	true
gptkbp:mutationAssociatedWith	gptkb:ALK_rearrangement gptkb:EGFR_mutation gptkb:KRAS_mutation
gptkbp:prevalence	most common in older adults
gptkbp:prognosis	stage at diagnosis performance status molecular markers generally poor
gptkbp:riskFactor	smoking asbestos exposure radon exposure
gptkbp:stageName	gptkb:TNM_staging
gptkbp:subspecies	gptkb:cancer gptkb:large_cell_carcinoma
gptkbp:symptom	weight loss cough shortness of breath chest pain hemoptysis
gptkbp:bfsParent	gptkb:HGNC:3767
gptkbp:bfsLayer	7